Project Twenty21 - August Update

Get Project Twenty21 Updates via Email <!doctype html>   Project Twenty21: August Update 16th August 2022 We’re doing some work behind the scenes to revamp the way our monthly T21 data update is laid out, so this month’s data points will be a little delayed and released as soon as they are ready – please bear with us!  …


The Drug Enforcement Agency listens to psychedelic experts

By Professor David Nutt and James Bunn The Drug Enforcement Agency (DEA) recently withdrew a proposal to ban five psychedelic substances: 4-Hydroxy-N,N-diisopropyltryptamine (4-OH-DiPT), 5-Methoxy-alphamethyltryptamine (5-MeO-AMT), N-Isopropyl-5-Methoxy-N-Methyltryptamine (5-MeO-MiPT), N,N-Diethyl-5-methoxytryptamine (5-MeO-DET), and N,N-Diisopropyltryptamine (DiPT). Earlier this year, the DEA proposed that these substances ought to be moved to schedule 1 (the most restrictive schedule in the Controlled  …


Comparative harms assessments for cannabis, alcohol, and tobacco: Risk for psychosis, cognitive impairment, and traffic accident

Author Petter Grahl Johnstad Published July 25, 2022 Abstract Researchers have associated cannabis use with risk for psychosis, cognitive impairment, and traffic accident. However, this review shows that the association between moderate cannabis use and psychosis is no stronger, and often considerably weaker, than the corresponding association for moderate tobacco use. The same holds for  …


State naloxone co-prescribing laws show mixed effects on overdose mortality rates

Author MaryKate Duska, Jared M. Rhoads, Elizabeth C. Saunders, Tracy Onega Published July 25, 2022 Objective To examine the relative changes in opioid overdose mortality rates between states that have and have not adopted naloxone co-prescribing laws. Methods We performed a synthetic control analysis. National Vital Statistics data for the years 2012–2018 were analysed, and  …


Project Twenty21 - July Update

Get Project Twenty21 Updates via Email Our Project Twenty21 monthly updates have changed. From now on, we will be incorporating the medical cannabis news (previously included in our T21 mailout) into the Drug Science newsletter which goes out around the first Tuesday of every month. This means that from next month you will receive a second  …


Diamorphine-Assisted Treatment

Diamorphine-assisted treatment is the prescription and provision of hygienic, medical-grade diamorphine to patients in a clinical set-up – patients attend a clinic and are dosed by a clinician once or twice a day depending on individual needs. Drug-related deaths in the UK have risen significantly over the past 10 years, with a steep increase in  …


The Misuse of Drugs Regulations 2001: A case study in poor legislative drafting

Author Cathal T Gallagher Published July 11, 2022 Abstract The Misuse of Drugs Regulations 2001 (MDRs) create exemptions to the offences of possession, production, supply, and administration of controlled drugs (CDs), which are necessary to allow healthcare professionals to treat patients without rendering themselves liable to prosecution for various offences under the Misuse of Drugs  …


Over One Hundred Years of MDMA Research

Written by Libby Furminger   History 3,4-Methylenedioxymethamphetamine (MDMA), also known as Mandy, Molly, Ecstasy or ‘E’, is a class A drug known for inducing feelings of happiness, chattiness, liveliness, and overall feelings of ecstasy, making it a common adjacent to enhancing raves, clubs and parties. Lesser known, MDMA has historically also been used in research  …


Professor Sir Colin Blakemore and Drug Science

“All of us at Drug Science were saddened to hear earlier this week of the death of Colin following his year-long battle with motor-neuron disease. Colin was instrumental in the founding of our charity in 2010, coming to the first planning meeting and staying with us as member, a trustee and finally a patron for  …


Cannabinoids and the endocannabinoid system in fibromyalgia: a review of preclinical and clinical research

Authors Stephanie Bourke, Anne Schlag, Saoirse Elizabeth O’Sullivan, David Nutt, David Finn Published May 21, 2022 Fibromyalgia affects millions of people worldwide and has a significant impact on quality of life. Fibromyalgia symptoms include persistent widespread pain, fatigue, stiffness, sleep disturbances and cognitive dysfunction. Endogenous cannabinoids (endocannabinoids), the body’s own marijuana-like transmitters, are involved in  …


Project Twenty21 - June Update

Get Project Twenty21 Updates via Email Project Twenty21 June Update The big news this month is that our Chronic Pain paper has been published! Using Project Twenty21 data, it looks at the characteristics of people seeking prescribed cannabinoids for the treatment of chronic pain. Our results demonstrate the complexities of studying chronic pain, and the  …


Characteristics of People Seeking Prescribed Cannabinoids for the Treatment of Chronic Pain: Evidence From Project Twenty 21

Authors Anne Katrin Schlag, Michael Lynskey, Alan Fayaz, Alkyoni Athanasiou-Fragkouli, Brigitta Brandner, Barbara Haja, Elizabeth Iveson and David J. Nutt Published June 14, 2022 Medical Cannabis for Chronic Pain Chronic pain is a pervasive, and potentially disabling condition. In the UK it is estimated to affect between one third and one half of the adult  …


The Post COVID cathinone hydra

Written by Professor Fiona Measham and Dr Michael Pascoe A study published in the journal of Drug Science Policy and Law describes tumultuous changes to the UK MDMA drug market following Brexit and COVID-19 lockdowns. In this first academic publication from The Loop’s ‘back of house’ testing service, nearly half of substances sold as MDMA were  …


Project Twenty21 - May Update

Get Project Twenty21 Updates via Email Project Twenty21 May Update We are well over the 2500 mark now with the number of patients registered with the project. Thank you for everything you do as supporters of Drug Science to help us spread the word about medical cannabis and Project Twenty21. Our research project with the University  …


UK Drugs Inquiry: Drug Science Response

In 2019, Drug Science submitted evidence to the Drugs Policy Inquiry by the Health and Social Care Committee. In 2020, we prepared a detailed report in response to the Dame Carol Black Drugs Review. In 2021, we reacted to the government’s 10-year Drug Strategy. Our 2022 response to the UK government’s call for evidence of  …


Secondary School Educational Resources

For far too long school students have been denied access to the truth about drugs, which has undermined their trust in health information in general and put them at greater risk of harm. This new initiative sets out to rectify this failure by presenting teaching materials that are evidence-based, balanced and proportionate. In this way,  …


Project Twenty21 - April Update

Get Project Twenty21 Updates via Email   Project Twenty21 April Update This month we’re celebrating another fantastic clinic joining us, plus some of the exciting events that we’re involved with in the coming weeks – including one organised by a Twenty21 patient. And there’s even more in the pipeline – as always, we’ll keep you fully up-to-date  …


Project Twenty21 - March Update

Get Project Twenty21 Updates via Email Spring is definitely here – our website has undergone a Spring-clean, we’re continuing to see encouraging results from our data analysis and there are lots of events (both virtual and in-person) on the horizon where we’ll be spreading the word about medical cannabis. We’ve got good news, that we’ve updated  …


Tripping over red tape: psychedelics for mental health

The last decade has seen a new focus on psychedelics as powerful medicines for treating severe mental health issues, including the use of psilocybin for conditions such as PTSD and treatment-resistant depression. However, many of these potentially life-saving treatments, including psilocybin, remain difficult to research due to overly strict drug laws. In this blog, Professor Jo  …


2022 Drug Trend Report: Time, Music, Clubbing, Age, and Diet

By Adam Winstock, Rasmus Munksgaard, Emma Davies, Jason Ferris, Ahnjili ZhuParris, Monica Barratt Full report can be found on The Global Drug Survey website.   Background People are not defined by the drugs they use. This report is based on our non-probability data collected from 592,000 people completing our online survey, over the last 7  …

Project Twenty21 - February Update

Get Project Twenty21 Updates via Email It’s been a very busy start to the year, with lots of change happening and expansion in the pipeline for the project – so there’s so much to update you on. We’ve got loads of events coming up, so scroll down to get them in your diary. As mentioned  …


What is DMT therapy?

By Dr Carol Routledge, Chief Medical & Scientific Officer at Small Pharma DMT-assisted therapy is a novel psychedelic therapy which aims to treat a whole suite of mental health problems that we have sadly come to take for granted as part of 21st century life. Early trials are investigating DMT-assisted therapy in the treatment of  …


DHSC announces that the UK will not legalise Snus

DHSC announces that it will not legalise the world’s most successful smoking substitute   The health department has stated that it will not legalise the oral nicotine product snus The product has driven the world’s most dramatic falls in smoking in Scandinavia It is popular among hardcore smokers who do not want to use inhaled  …


Medical Cannabis study Project Twenty21 begins in Australia

7th February 2021 Drug Science’s large scale observational study of medical cannabis has opened its first non-UK operation in Australia Known as Project Twenty21 Australia, it will be run in collaboration with the Australasian College of Cannabinoid Medicine (also known as ACCM, and the research arm of Releaf Group Ltd).   Operational since 2019 in  …


Driving Performance and Cannabis Users’ Perception of Safety - Review

By Dr Michael White – Adjunct Senior Fellow, School of Psychology, University of Adelaide, South Australia Marcotte et al. (2022): Per se laws are unjust One of the best cannabis-impairment studies that I have encountered (Marcotte et al., 2022) was published online this week, as an open-access article. You can read it here: Driving Performance and  …


Why doctors have a moral imperative to prescribe and support medical cannabis—an essay by David Nutt

Authors David J Nutt Published January 26, 2022 “Medical cannabis has been legal to prescribe since 2018—yet just a handful of prescriptions have been made in three years. The reasons: stigma, fear, and an entrenched resistance in the medical profession that is harming patients” Prof David Nutt – Founder of Drug Science The field of  …