69. Amphetamine, Heroin and Cocaine with Prof Aldo Badiani


This week’s episode features Professor Aldo Badiani who is Professor of Pharmacology at the Department of Physiology and Pharmacology of Sapienza University of Rome (Italy). Professor Badiani received his doctoral degree in Medicine and Surgery from Sapienza University of Rome and carried out post-doctoral research in Italy (CNR), Canada (CSBN), and USA (University of Michigan) to then return to Sapienza University Medical School as Assistant Professor in the Department of Pharmacology, progressing to the rank of Full Professor in 2008. At Sapienza he also served as Associate Chief Physician in the Drug Addiction unit of the University Hospital. Additionally, he has been President of the European Behavioural Pharmacology Society (EBPS) from 2011 to 2013.

Professor Badiani conducts research in the field of drug addiction with the focus on the role of environmental factors in determining individual vulnerability to drug addiction in both humans and animals. In this episode of Drug Science podcast you’ll learn about the most recent research on the science of drug addiction from a leading expert in the field.

Jane Stewart


Terry Robinson



Drug sensitization (reverse tolerance)



Incentive sensitization theory of addiction 

Kent C Berridge



Adrenal gland

Huda Akil


Nucleus accumbens

Frontal cortex



Naloxone precipitated withdrawal increases dopamine release in the dorsal striatum of opioid dependent men

Russell’s Circumplex Models