How does MDMA actually work? Our new study recruits psychotherapists to help answer that question
Of all the psychedelic treatments now under investigation, MDMA-assisted psychotherapy is among the most advanced. Two Phase III trials have supported its efficacy and safety for post-traumatic stress disorder (PTSD), and by the usual standards it met or exceeded the bar for a treatment to be considered empirically supported. Even so, in 2024 the US Food and Drug Administration (FDA) declined to approve it, citing a range of limitations.