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The current mechanisms in the United States to research and develop novel reversal agents for substances that can lead to overdose are restricted by regulations placed on the pharmaceutical industry.

To date, there has been a lack of consensus in the field of psychedelic research regarding key terms. It is our hope that development of this lexicon can aid in translating findings across various research groups and improve clarity and precision in our communications with each other and the general public.

Psychedelic-assisted therapy (PAT) is an emerging treatment that combines pharmacotherapeutic dosing sessions with psychotherapy. Despite limited regulatory approval, treatment seekers can access PAT through various avenues, including ketamine treatment centers and “supported adult use” psilocybin centers in the US, drug tourism, “underground” therapy, and participation in clinical trials.

Substance use at UK music festivals presents a significant public health challenge, with evolving patterns of drug use, associated risk behaviours, and harm reduction practices among attendees.

The number of cannabis-related arrests has been increasing in Japan, accompanied by the implementation of stricter legal penalties. However, there has been little investigation into the motivations behind cannabis use or the reasons for continued use among users in Japan.

In 1996, Purdue Pharmaceutical's (Purdue) launched OxyContin, an opioid painkiller, with the largest marketing strategy in pharmaceutical history. Literature has now established that Purdue's marketing of OxyContin was a root cause of the current opioid crisis, responsible for over 600,000 deaths in and beyond North America.

Opioid-related deaths in Ontario remain persistently high, driven largely by an unstable and unregulated drug supply. In response, harm reduction services, such as supervised consumption sites/consumption and treatment services and safer supply programs, have been implemented to reduce the risks of overdose and connect people who use drugs with essential healthcare and social services.

A 2019 study revealed more than 80 products available online with implied benefits to alcohol hangover. Since then, several developments may have influenced the market.

This article discusses how unintended side effects from the international regime of drug criminalization may serve to increase harmful drug use among some population segments and performs systematic scoping reviews of two putative underlying dynamics relating to violence victimization and the forbidden fruit or psychological reactance effect.

Current regulation frameworks for medicines struggle to address the combination of pharmacological and psychotherapeutic elements in psychedelic therapy.

Stigmatised attitudes, opinions on opioid use, and prior contact with People Who Use Drugs (PWUD) contribute to what policies are publicly supported and implemented to reduce drug-related deaths. This study examined how these variables relate to policy support for the implementation of supervised injection sites, laws protecting bystanders at the scene of an overdose, and over-the-counter naloxone.

We sought to examine nascent trends surrounding the impacts of police drug seizures in the period after a substantial public policy shift surrounding the personal possession of drugs in British Columbia (BC), Canada. We explored the intersection of drug testing and police opioid seizures in Vancouver, BC.

The global regulatory landscape for psilocybin and PSILO-AT remains highly variable, with significant differences in the scope and clarity of medical governance.

Although there is growing support for the protective effects of psychedelics on mental health, recent evidence finds racial and ethnic minorities gain fewer benefits.

The increasing incidence of opioid dependence linked to the consumption of unwashed poppy seeds (UPSs) is an emerging public health concern.

A recent meta-analysis in Drug Science, Policy and Law on the risk associated with the detection of tetrahydrocannabinol (THC) in blood and

This paper discusses the topic of safer injecting facilities with those who are likely to use them. Whilst more countries are adopting this

This article discusses the introduction of the safe drug consumption facility in Glasgow and considers some of its potential consequences.

In the UK, there are over 40,000 specialist clinicians who are eligible to prescribe cannabis-based medical products (CBMPs); however, only

This paper delves into the crucial yet complex relationship between federal laws and scientific research, centering on the Controlled Substa

MDMA (now called midomafetamine by the FDA) is a substituted amphetamine first synthesised in 1912 by Merck that has been developed over the